Reproductive aging is associated with changes in oocyte mitochondrial dynamics, function, and mtDNA quantity
نویسندگان
چکیده
منابع مشابه
Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging
Female reproductive capacity declines dramatically in the fourth decade of life as a result of an age-related decrease in oocyte quality and quantity. The primary causes of reproductive aging and the molecular factors responsible for decreased oocyte quality remain elusive. Here, we show that aging of the female germ line is accompanied by mitochondrial dysfunction associated with decreased oxi...
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ژورنال
عنوان ژورنال: Maturitas
سال: 2016
ISSN: 0378-5122
DOI: 10.1016/j.maturitas.2016.06.015